Tag: genetics
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Undifferentiated pleomorphic sarcoma (UPS) of the bone FactFile
Overview of Undifferentiated pleomorphic sarcoma (UPS) of the bone Other names: Previously called malignant fibrous histocytoma. Malignancy: Malignant and fast-growing mesenchymal tumour. Type of bone tumour: Primary Grade: High and can metastasize in 50% of cases. Extremely rare (2 – 6% of all primary malignant bone tumours. Location: Long bones: femur (lower limb/thigh bone). Tibia and…
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Osteoblastoma FactFile
Overview of Osteoblastoma Malignancy: Benign Type of bone tumour: Primary Grade: Low Location: It affects the skull and vertebraeLarger than osteoma – The central nidus is more than 2cm References Bădilă, A.E., Rădulescu, D.M., Niculescu, A.-G., Grumezescu, A.M., Rădulescu, M. and Rădulescu, A.R. (2021). Recent Advances in the Treatment of Bone Metastases and Primary Bone Tumors:…
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Osteoid Osteoma FactFile
Overview of Osteoid Osteoma Malignancy: Benign Type of bone tumour: Primary Grade: Low Location: It mainly occurs in the long bones. Upper limbs and hands: Humerus (arms), fingers (phalanges) Lower limbs: Proximal femur, tibia, feet (phalanges) Posterior of spine (vertebrae) Onset: First two decades (5 to 25) Risk Factors Of Osteoid Osteoma A) Genetics: Adenomatous Polyposis…
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Recent Advances In Understanding The Link Between BRCA Gene Testing And Prostate Cancer
The continual rise of prostate cancer cases worldwide has shifted its ranking from being the second most common cancer to the leading malignancy in males. This corresponds to high morbidity and mortality in recent years (Zannini et al., 2025). The prostate gland is part of the male reproductive system, situated under the bladder, and primarily…
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A Novel Genetic Test Using Nanopore-based assay
Nanopore genetic sequencing is an innovative technique where the graphical interface software Rapid nanpOre Brain IntraoperatIve classificatioN (ROBIN) presents sequencing results of patients in real-time as data is being analysed and interpreted from a single assay (Deacon et al., 2025). The World Health Organisation (WHO) classification of tumours of the central nervous system (CNS) has…
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What Are The Causes And Risk Factors Of Cancer?
Original author: Dr Shraddha Bhange Original published date: 6th March 2014 Article updated by: Dr Hafsa Waseela Abbas Update date: April 2025 Review date: April 2027 About Dr Shraddha Bhange is a trained doctor and experienced safety physician. She is also one of the Board members of the ThinkSharp Foundation. Upon setting up the FST…
The Farah Saeed Project 