Tag: mesenchymal
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Undifferentiated pleomorphic sarcoma (UPS) of the bone FactFile
Overview of Undifferentiated pleomorphic sarcoma (UPS) of the bone Other names: Previously called malignant fibrous histocytoma. Malignancy: Malignant and fast-growing mesenchymal tumour. Type of bone tumour: Primary Grade: High and can metastasize in 50% of cases. Extremely rare (2 – 6% of all primary malignant bone tumours. Location: Long bones: femur (lower limb/thigh bone). Tibia and…
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Round Cell Sarcoma FactFile
Overview of Round Cell Sarcoma Malignancy: Malignant Type of bone tumour: Mesenchymal tumour Grade: Varies Location: Onset: Varies with type of round cell sarcoma Risk Factors Of Round Cell Sarcoma A) Genetics: EWSR1::NFATC2 and FUS::NFATC2 fusions EWS RNA-binding protein 1 (EWSR1) is a member of the FET or TET family and is found on chromosome…