Tag: dna
-
Giant Cell Tumour Of The Bone FactFile
Overview of Giant Cell Tumour Of The Bone Malignancy: Benign; aggressive; rarely metastasizes. 20% of benign skeletal tumours. Type of bone tumour: Primary 5% of all primary tumours Grade: Varies Location: Multiple Most lesions (75% to 90%) form on the extension of metaphysis into epiphysis of long bones. For instance, the frequent areas: distal femur (thigh…
-
Osteosarcoma FactFile Part A (Genetic Syndromes)
Overview of Osteosarcoma It is also known as osteogenic sarcoma Malignancy: Most common type of bone cancer. Secondary growth can occur in the lungs (pulmonary) and is characterised by M2-like tumour-associated macrophages (TAMS) in the tumour stroma. Stroma is the connective tissue that forms the basis of the cell or tissue. Macrophages are a type of…
-
Novel Therapeutic Interventions For The Treatment Of Prostate Cancer
Prostate cancer is the most common cancer that affects the male population. National Institute for Health and Care Excellence (2026) revealed that prostate cancer accounted for 46000 cases in England and Wales between 2019 and 2020. 13% of these cases have progressed to metastasis at diagnosis. There are ca. 12,000 deaths linked to prostate cancer…
-
A Novel Genetic Test Using Nanopore-based assay
Nanopore genetic sequencing is an innovative technique where the graphical interface software Rapid nanpOre Brain IntraoperatIve classificatioN (ROBIN) presents sequencing results of patients in real-time as data is being analysed and interpreted from a single assay (Deacon et al., 2025). The World Health Organisation (WHO) classification of tumours of the central nervous system (CNS) has…