Tag: dna
-
Giant Cell Tumour Of The Bone FactFile
Overview of Giant Cell Tumour Of The Bone Malignancy: Benign; aggressive; rarely metastasizes. 20% of benign skeletal tumours. Type of bone tumour: Primary 5% of all primary tumours Grade: Varies Location: Multiple Most lesions (75% to 90%) form on the extension of metaphysis into epiphysis of long bones. For instance, the frequent areas: distal femur (thigh…
-
Osteosarcoma FactFile Part A (Genetic Syndromes)
Risk Factors Of Osteosarcoma Part A A) Genetic Syndromes There are many genetic syndromes that increase the risk and is associated with osteosarcoma. Here are some of them Li Fraumeni Syndrome It is an autosomal dominant disorder. Autosomal refers to the 22 pairs of numbered chromosomes in humans that are not involved in determining biological…
-
Novel Therapeutic Interventions For The Treatment Of Prostate Cancer
Prostate cancer is the most common cancer that affects the male population. National Institute for Health and Care Excellence (2026) revealed that prostate cancer accounted for 46000 cases in England and Wales between 2019 and 2020. 13% of these cases have progressed to metastasis at diagnosis. There are ca. 12,000 deaths linked to prostate cancer…
-
A Novel Genetic Test Using Nanopore-based assay
Nanopore genetic sequencing is an innovative technique where the graphical interface software Rapid nanpOre Brain IntraoperatIve classificatioN (ROBIN) presents sequencing results of patients in real-time as data is being analysed and interpreted from a single assay (Deacon et al., 2025). The World Health Organisation (WHO) classification of tumours of the central nervous system (CNS) has…