Tag: osteosarcoma
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Appearance Of Osteosarcoma Under The Microscope
Appearance Under Microscope Cell Morphology: pleomorphic and spindle Pleomorphic: a cell appears in different forms. Fine lacey pattern of the trabeculae. Irregular clumps of osteoid. Types of Histology Histology is the study of tissues. Supporting Image Resources References Bădilă, A.E., Rădulescu, D.M., Niculescu, A.-G., Grumezescu, A.M., Rădulescu, M. and Rădulescu, A.R. (2021). Recent Advances in…
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Osteosarcoma FactFile Part B (Other Risk Factors)
Other risk factors of Osteosarcoma B) Predisposed conditions: Paget’s Disease Abnormal bone remodelling where there is either excessive bone formation or breakdown. There is a high proportion of spongy bone to compact bone. Low production of minerals causes weakening of bones with a spotty appearance. Other effects of Paget’s disease Osteoclast activity decreases -> This…
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Osteosarcoma FactFile Overview
Overview of Osteosarcoma It is also known as osteogenic sarcoma Malignancy: Most common type of bone cancer. Secondary growth can occur in the lungs (pulmonary) and is characterised by M2-like tumour-associated macrophages (TAMS) in the tumour stroma. Stroma is the connective tissue that forms the basis of the cell or tissue. Macrophages are a type of…
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Osteosarcoma FactFile Part A (Genetic Syndromes)
Risk Factors Of Osteosarcoma Part A A) Genetic Syndromes There are many genetic syndromes that increase the risk and is associated with osteosarcoma. Here are some of them Li Fraumeni Syndrome It is an autosomal dominant disorder. Autosomal refers to the 22 pairs of numbered chromosomes in humans that are not involved in determining biological…
The Farah Saeed Project 