Tag: oncology
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Osteosarcoma FactFile Overview
Overview of Osteosarcoma It is also known as osteogenic sarcoma Malignancy: Most common type of bone cancer. Secondary growth can occur in the lungs (pulmonary) and is characterised by M2-like tumour-associated macrophages (TAMS) in the tumour stroma. Stroma is the connective tissue that forms the basis of the cell or tissue. Macrophages are a type of…
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Osteosarcoma FactFile Part A (Genetic Syndromes)
Risk Factors Of Osteosarcoma Part A A) Genetic Syndromes There are many genetic syndromes that increase the risk and is associated with osteosarcoma. Here are some of them Li Fraumeni Syndrome It is an autosomal dominant disorder. Autosomal refers to the 22 pairs of numbered chromosomes in humans that are not involved in determining biological…
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Ewing Sarcoma FactFile
Overview of Ewing Sarcoma Malignancy: Rare Type of bone tumour: Primary Grade: high (aggressive type) Location: Onset: First three decades (Within 30 years) – children, teenagers, and young adults. Median age at diagnosis: 15 years Appearance: Onion skin Risk Factors Of Ewing Sarcoma A) Genetics: The rearrangement between FET or TET family genes AND the…
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Novel Therapeutic Interventions For The Treatment Of Prostate Cancer
Prostate cancer is the most common cancer that affects the male population. National Institute for Health and Care Excellence (2026) revealed that prostate cancer accounted for 46000 cases in England and Wales between 2019 and 2020. 13% of these cases have progressed to metastasis at diagnosis. There are ca. 12,000 deaths linked to prostate cancer…
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Recent Advances In Understanding The Link Between BRCA Gene Testing And Prostate Cancer
The continual rise of prostate cancer cases worldwide has shifted its ranking from being the second most common cancer to the leading malignancy in males. This corresponds to high morbidity and mortality in recent years (Zannini et al., 2025). The prostate gland is part of the male reproductive system, situated under the bladder, and primarily…
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The role of Cannabis compounds in the treatment of ovarian cancer
Ovarian cancer is one of the most critical health concerns in the female population worldwide. It is the most common gynaecological malignancy, often detected late due to non-specific symptoms at early stages. It has been reported that two of the main bioactive compounds that originate from the Cannabis sativa plant, cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC),…
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Bevacizumab – A useful treatment for Colorectal Cancer in combination with chemotherapy
Colorectal cancer is the third most common cancer globally (World Health Organisation, 2026). It is more common in the male population, and the risk increases with age. It is estimated that 35, 000 people are diagnosed with colorectal cancer in England annually (National Institute for Health Care and Excellence, 2025). The National Health Service bowel…
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New Monoclonal Antibodies For The Treatment Of Ovarian Cancer
Ovarian cancer presents the highest rate of morbidity and mortality due to its non-specific symptoms in the early stages and its silent nature. Since the invention of hybridoma technology in 1975 by Köhler and Milstein to generate murine monoclonal antibodies, a mass effort was made to design new engineering strategies to maintain demand, efficacy, and…
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Do low and middle-income countries increase cancer death rates?
The World Health Organisation has reported that over 70% of cancer deaths globally disproportionately occur in low and middle-income countries (LMIC). The rising global burden is caused by profound inequitable challenges from limited healthcare resources, lack of public awareness of cancers and their prevention, and inadequate training of healthcare staff, which creates a fragile health…
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The Role Of Artificial Biomarkers In The Diagnosis And Treatment Of Neurological Tumours
The emergence of Artificial Intelligence (AI) has had a mass transformative effect in shifting healthcare to a positive enlightenment, particularly in neuro-oncology, where it empowered healthcare professionals to diagnose patient cases more efficiently, strengthen prognosis, and enable real-time monitoring and treatment planning (Khalighi et al., 2024). This helped improve the overall clinical outcomes of cancer…
The Farah Saeed Project 