Category: Uncategorized
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Osteoblastoma FactFile
Overview of Osteoblastoma Malignancy: Benign Type of bone tumour: Primary Grade: Low Location: It affects the skull and vertebraeLarger than osteoma – The central nidus is more than 2cm References Bădilă, A.E., Rădulescu, D.M., Niculescu, A.-G., Grumezescu, A.M., Rădulescu, M. and Rădulescu, A.R. (2021). Recent Advances in the Treatment of Bone Metastases and Primary Bone Tumors:…
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Osteoid Osteoma FactFile
Overview of Osteoid Osteoma Malignancy: Benign Type of bone tumour: Primary Grade: Low Location: It mainly occurs in the long bones. Upper limbs and hands: Humerus (arms), fingers (phalanges) Lower limbs: Proximal femur, tibia, feet (phalanges) Posterior of spine (vertebrae) Onset: First two decades (5 to 25) Risk Factors Of Osteoid Osteoma A) Genetics: Adenomatous Polyposis…
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Appearance Of Osteosarcoma Under The Microscope
Appearance Under Microscope Cell Morphology: pleomorphic and spindle Pleomorphic: a cell appears in different forms. Fine lacey pattern of the trabeculae. Irregular clumps of osteoid. Types of Histology Histology is the study of tissues. Supporting Image Resources References Bădilă, A.E., Rădulescu, D.M., Niculescu, A.-G., Grumezescu, A.M., Rădulescu, M. and Rădulescu, A.R. (2021). Recent Advances in…
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Osteosarcoma FactFile Part B (Other Risk Factors)
Other risk factors of Osteosarcoma B) Predisposed conditions: Paget’s Disease Abnormal bone remodelling where there is either excessive bone formation or breakdown. There is a high proportion of spongy bone to compact bone. Low production of minerals causes weakening of bones with a spotty appearance. Other effects of Paget’s disease Osteoclast activity decreases -> This…
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Osteosarcoma FactFile Overview
Overview of Osteosarcoma It is also known as osteogenic sarcoma Malignancy: Most common type of bone cancer. Secondary growth can occur in the lungs (pulmonary) and is characterised by M2-like tumour-associated macrophages (TAMS) in the tumour stroma. Stroma is the connective tissue that forms the basis of the cell or tissue. Macrophages are a type of…
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Osteosarcoma FactFile Part A (Genetic Syndromes)
Overview of Osteosarcoma It is also known as osteogenic sarcoma Malignancy: Most common type of bone cancer. Secondary growth can occur in the lungs (pulmonary) and is characterised by M2-like tumour-associated macrophages (TAMS) in the tumour stroma. Stroma is the connective tissue that forms the basis of the cell or tissue. Macrophages are a type of…
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Ewing Sarcoma FactFile
Overview of Ewing Sarcoma Malignancy: Rare Type of bone tumour: Primary Grade: high (aggressive type) Location: Onset: First three decades (Within 30 years) – children, teenagers, and young adults. Median age at diagnosis: 15 years Appearance: Onion skin Risk Factors Of Ewing Sarcoma A) Genetics: The rearrangement between FET or TET family genes AND the…
The Farah Saeed Project 